AUTHOR: IBE, JOY IJEOMA (MSc)
DEPARTMENT: INDUSTRIAL MICROBIOLOGY
AFFILIATION: FEDERAL UNIVERSITY OF TECHNOLOGY OWERRI, NIGERIA
Quality changes associated with on-the-shelf paediatric syrups and infusions were determined. Pour plate, Millipore filtration and other microbiological and physiochemical techniques were adopted. Expired and unexpired paediatric syrups viz. ventolin, Benylin, Chloroquin and Actifed were found to be contaminated by bacteria and fungal isolates, with the expired paediatric syrups formaula harbouring more bacterial and fungal contaminants. Mosegor was only contaminated by bacteria. Benylin had highest becaterial and fungal loads of 5.0×103 and 6.3×102 and 1.0 x102cfu/ml, for the unexpired and expired samples respectively. Analysis of drip water revealed no bacterial and fungal contaminants while the injection water samples were contaminated by bacteria. Identification tests revealed the isolation of Bacillus, Staphyloccoccus, Escherihia, Klebsiella, Pseudomonas, Penicillium, Curvularia, Rhizopus, Trichophyton and Aspergillus. Percentage occurrence of the isolates revealed that benylin and Ventolin had the least and highest levels of 9.1% and 45.5% respectively. Antibiotic sensitivity bioassay of isolates indicated that 20-70% and 10-60% of the gram positive and Gram negative isolates respectively. Obvious parity was recorded in colour and pH of the expired and unexpired syrups. This study reveals poor public health status of some on-the-shelf paediatric syrups and injection water, which demands urgent attention.
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